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Before Patrick Mahomes laced up his cleats for his 2026-2027 NFL regular-season debut, US prediction markets had already cleared a historic benchmark for the opening week of the season.

Two operators alone – Kalshi and Polymarket – topped the combined $1 billion mark in NFL trading activity over the first six days of Week 1, according to numerous measures this week. During the period, Kalshi recorded NFL volume of $983.4 million, according to DeFi Rate, earning the pole position by a large margin. Mahomes and the Kansas City Chiefs thrashed the Denver Broncos 31-10 on Monday Night Football, capping the largest week for prediction markets ever.

Even before the primetime matchup in Kansas City, it became abundantly clear that the industry would shatter previous marks for weekly activity. The AFC West showdown bolstered the already robust totals. Overall, volume for the week hit a record $15.9 billion, according to Bank of America, up 16% from a week earlier.

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Touch Sokhak, deputy spokesperson of the Ministry of Interior, emphasised that the operation seeks to prevent Cambodia from becoming “a safe haven or money-laundering base for technology-related criminals”.

However, the sustained enforcement drive has already taken a toll on the wider Cambodian economy. In May, the government lowered its 2026 GDP growth forecast as construction, real estate and consumer spending absorb the short-term impact of the crackdown.

Meanwhile, the CGMC has not disclosed when the integrity and quality framework will be finalised, leaving casino operators without concrete guidance on the new requirements. 

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“Our aim is to create an environment in which regulators, operators and suppliers can engage constructively on the opportunities and challenges facing the industry across the continent,” Kesitilwe stated.

Collaboration was a key focus of the inaugural Africa Safer Gambling Week, which the AiA hosted last week.

Kesitilwe told iGB an important theme of the event was fostering year-round collaboration and turning conversations on safer gambling into practical measures.